Combine the flour, baking powder and salt in a bowl. In a separate bowl, cream the butter with an electric mixer until pale and fluffy. Add the sugar and beat until combined. Add the vanilla extract, eggs and beat until fully incorporated. Add the dry ingredients in 2 additions, alternating with the milk.
Divide the mixture into 4 bowls and dye the batter pink, blue and yellow, leaving the remaining bowl white. Grease a skull-shaped baking pan and add dollops of the different shades of batter. Bake at 350F for 30-40 minutes, or until a skewer inserted into the cake comes out clean. Cool for 10 minutes in the pan, then transfer to a wire rack and cool completely.
Once the cakes have fully cooled, slice any excess cake off the bottom to allow the cakes to sit flat. Transfer the cakes to a wire rack with a sheet of parchment paper placed underneath.